Intended for US audience only

How Optune Lua Works

Optune Lua^® works by creating Tumor Treating Fields (TTFields), which are electric fields that disrupt cancer cell division.

Using 4 adhesive patches called transducer arrays, TTFields therapy is delivered right into the area of your body where the cancer is located. TTFields may destroy some cancer cells completely and have not been shown to affect healthy cells.

How MPM cancer cells divide and multiply

MPM cancer cell

MPM cancer cell begins to divide

More and more cancer cell appear

Optune Lua interferes with MPM cancer cell division

Optune Lua creates TTFields, which interfere with the dividing MPM cancer cell

TTFields may slow down or stop MPM cancer cell division

TTFields may cause cancer cells to be destroyed

Optune Lua delivers treatment with TTFields right where the MPM cancer cells are located

Optune Lua delivers TTFields to the area of your body with cancer through arrays, which are adhesive patches that stick to your skin
Where you put the arrays on your body matters. Each person’s body is a different shape and size and may have cancer cells in different locations. You (and your care partner) will receive training by a Novocure^® Device Support Specialist to show you how and where to place the arrays on your upper body

Sample placement of arrays

Contact Novocure to see how to place arrays for MPM.

Note: For some people, this may include the placement of arrays on the side of the body.

Treating MPM with Optune Lua may help.

Explore the Optune Lua System

What should not use Optune Lua?

Optune Lua is not for everyone. Talk to your doctor if you have:

An implanted electronic medical device including a pacemaker, implantable automatic defibrillator, etc. Optune Lua has not been tested in people with implanted electronic devices, which may cause the devices not to work properly

A known sensitivity to conductive hydrogels (the gel on the arrays placed on the upper body like the ones used on EKGs). When Optune Lua comes into contact with the skin, it may cause more redness and itching or may rarely cause a life-threatening allergic reaction

Do not use Optune Lua if you are pregnant or are planning to become pregnant. It is not known if Optune Lua is safe or effective during pregnancy.

What should I know before using Optune Lua?

Optune Lua should only be used after receiving training from qualified personnel, such as your doctor, a nurse, or other medical staff who have completed a training course given by Novocure^®, the maker of Optune Lua.

Do not use any parts that did not come with Optune Lua sent to you by Novocure or given to you by your doctor

Do not get the device or transducer arrays wet

Please be aware that Optune Lua has a cord that may cause tripping when connected to an electric socket

If you have an underlying serious skin condition on the upper body, discuss with your doctor whether this may prevent or temporarily interfere with the Optune Lua treatment

What are the possible side effects of Optune Lua?

Most common side effects of Optune Lua when used together with chemotherapy were low red blood cell count, constipation, nausea, tiredness, chest pain, fatigue, skin irritation from device use, itchy skin, and cough.

Other potential adverse effects associated with the use of Optune Lua include: treatment related skin irritation, allergic reaction to the plaster or to the gel, electrode overheating leading to pain and/or local skin burns, infections at sites of electrode contact with the skin, local warmth and tingling sensation beneath the electrodes, muscle twitching, medical device site reaction and skin breakdown/skin ulcer.

Talk to your doctor if you have any of these side effects or questions.

Please click here to see the Optune Lua Instructions For Use (IFU) for complete information regarding the device’s indications, contraindications, warnings and precautions.